Genetic Regulation of Tryptase Production and Clinical Impact: Hereditary Alpha Tryptasemia, Mastocytosis and Beyond

Tryptase is a serine protease that is predominantly produced by tissue mast cells (MCs) and stored in secretory granules together with other pre-formed mediators. MC activation, degranulation and mediator release contribute to various immunological processes, but also to several specific diseases, s...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Sprinzl, Bettina, Greiner, Georg, Uyanik, Goekhan, Arock, Michel, Haferlach, Torsten, Sperr, Wolfgang R., Valent, Peter, Hoermann, Gregor
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957558/
https://ncbi.nlm.nih.gov/pubmed/33671092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052458
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