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Digital PCR: A Sensitive and Precise Method for KIT D816V Quantification in Mastocytosis

BACKGROUND: The analytically sensitive detection of KIT D816V in blood and bone marrow is important for diagnosing systemic mastocytosis (SM). Additionally, precise quantification of the KIT D816V variant allele fraction (VAF) is relevant clinically because it helps to predict multilineage involveme...

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Bibliografiske detaljer
Udgivet i:Clin Chem
Main Authors: Greiner, Georg, Gurbisz, Michael, Ratzinger, Franz, Witzeneder, Nadine, Simonitsch-Klupp, Ingrid, Mitterbauer-Hohendanner, Gerlinde, Mayerhofer, Matthias, Müllauer, Leonhard, Sperr, Wolfgang R., Valent, Peter, Hoermann, Gregor
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115889/
https://ncbi.nlm.nih.gov/pubmed/29237714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2017.277897
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