Molecular quantification of tissue disease burden is a new biomarker and independent predictor of survival in mastocytosis

A high allele burden of the KIT D816V mutation in peripheral blood or bone marrow aspirates indicates multi-lineage hematopoietic involvement and has been associated with an aggressive clinical course of systemic mastocytosis. Since mast cells are substantially underrepresented in these liquid speci...

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Pubblicato in:Haematologica
Autori principali: Greiner, Georg, Gurbisz, Michael, Ratzinger, Franz, Witzeneder, Nadine, Class, Svenja Verena, Eisenwort, Gregor, Simonitsch-Klupp, Ingrid, Esterbauer, Harald, Mayerhofer, Matthias, Müllauer, Leonhard, Sperr, Wolfgang R., Valent, Peter, Hoermann, Gregor
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012478/
https://ncbi.nlm.nih.gov/pubmed/31018976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.217950
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