The KIT D816V allele burden predicts survival in patients with mastocytosis and correlates with the WHO type of the disease

KIT D816V is present in a majority of patients with systemic mastocytosis (SM). We determined the KIT D816V allele burden by quantitative real-time PCR in bone marrow and peripheral blood of 105 patients with mastocytosis. KIT D816V was detected in 92/105 patients (88%). Significant differences in t...

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Vydáno v:Allergy
Hlavní autoři: Hoermann, Gregor, Gleixner, Karoline V., Dinu, Graziella E., Kundi, Michael, Greiner, Georg, Wimazal, Friedrich, Hadzijusufovic, Emir, Mitterbauer, Gerlinde, Mannhalter, Christine, Valent, Peter, Sperr, Wolfgang R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896381/
https://ncbi.nlm.nih.gov/pubmed/24750133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.12409
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