Osteopontin Blockade Immunotherapy Increases Cytotoxic T Lymphocyte Lytic Activity and Suppresses Colon Tumor Progression

SIMPLE SUMMARY: Despite the breakthrough in human cancer immunotherapy, colorectal cancer, except for the small subset of microsatellite instable colorectal cancer (MSI, ~4% total cases), is one of the few human cancers that does not respond to current immune checkpoint inhibitor (ICI) immunotherapy...

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Udgivet i:Cancers (Basel)
Main Authors: Klement, John D., Poschel, Dakota B., Lu, Chunwan, Merting, Alyssa D., Yang, Dafeng, Redd, Priscilla S., Liu, Kebin
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957528/
https://ncbi.nlm.nih.gov/pubmed/33670921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13051006
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