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Loss of Fas Expression and Function is Coupled with Colon Cancer Resistance to Immune Checkpoint Inhibitor Immunotherapy

Despite the remarkable efficacy of immune checkpoint inhibitor (ICI) immunotherapy in various types of human cancers, colon cancer, except for the approximately 4% microsatellite-instable (MSI) colon cancer, does not respond to ICI immunotherapy. ICI acts through activating cytotoxic T lymphocytes (...

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Bibliografiske detaljer
Udgivet i:Mol Cancer Res
Main Authors: Xiao, Wei, Ibrahim, Mohammed L, Redd, Priscilla S., Klement, John D., Lu, Chunwan, Yang, Dafeng, Savage, Natasha M., Liu, Kebin
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359951/
https://ncbi.nlm.nih.gov/pubmed/30429213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-0455
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