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Loss of Fas Expression and Function is Coupled with Colon Cancer Resistance to Immune Checkpoint Inhibitor Immunotherapy

Despite the remarkable efficacy of immune checkpoint inhibitor (ICI) immunotherapy in various types of human cancers, colon cancer, except for the approximately 4% microsatellite-instable (MSI) colon cancer, does not respond to ICI immunotherapy. ICI acts through activating cytotoxic T lymphocytes (...

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Publicat a:Mol Cancer Res
Autors principals: Xiao, Wei, Ibrahim, Mohammed L, Redd, Priscilla S., Klement, John D., Lu, Chunwan, Yang, Dafeng, Savage, Natasha M., Liu, Kebin
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359951/
https://ncbi.nlm.nih.gov/pubmed/30429213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-0455
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