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Loss of Fas Expression and Function is Coupled with Colon Cancer Resistance to Immune Checkpoint Inhibitor Immunotherapy

Despite the remarkable efficacy of immune checkpoint inhibitor (ICI) immunotherapy in various types of human cancers, colon cancer, except for the approximately 4% microsatellite-instable (MSI) colon cancer, does not respond to ICI immunotherapy. ICI acts through activating cytotoxic T lymphocytes (...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Xiao, Wei, Ibrahim, Mohammed L, Redd, Priscilla S., Klement, John D., Lu, Chunwan, Yang, Dafeng, Savage, Natasha M., Liu, Kebin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6359951/
https://ncbi.nlm.nih.gov/pubmed/30429213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-0455
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