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Fibrinogen Interaction with Astrocyte ICAM-1 and PrP(C) Results in the Generation of ROS and Neuronal Death
Many neuroinflammatory diseases, like traumatic brain injury (TBI), are associated with an elevated level of fibrinogen and short-term memory (STM) impairment. We found that during TBI, extravasated fibrinogen deposited in vasculo-astrocyte interfaces, which was associated with neurodegeneration and...
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| Publié dans: | Int J Mol Sci |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7957521/ https://ncbi.nlm.nih.gov/pubmed/33673626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052391 |
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