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Quaternary Structure Changes for PrP(Sc) Predate PrP(C) Downregulation and Neuronal Death During Progression of Experimental Scrapie Disease
Prion diseases are fatal neurodegenerative diseases in mammals with the unique characteristics of misfolding and aggregation of the cellular prion protein (PrP(C)) to the scrapie prion (PrP(Sc)). Although neuroinflammation and neuronal loss feature within the disease process, the details of PrP(C)/P...
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| Yayımlandı: | Mol Neurobiol |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Springer US
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7695655/ https://ncbi.nlm.nih.gov/pubmed/32959170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-020-02112-z |
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