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Molecular Determinants of the Kinetic Binding Properties of Antihistamines at the Histamine H(1) Receptors
The binding affinity of ligands for their receptors is determined by their kinetic and thermodynamic binding properties. Kinetic analyses of the rate constants of association and dissociation (k(on) and k(off), respectively) of antihistamines have suggested that second-generation antihistamines have...
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| Udgivet i: | Int J Mol Sci |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7957501/ https://ncbi.nlm.nih.gov/pubmed/33673686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052400 |
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