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Molecular Determinants of the Kinetic Binding Properties of Antihistamines at the Histamine H(1) Receptors

The binding affinity of ligands for their receptors is determined by their kinetic and thermodynamic binding properties. Kinetic analyses of the rate constants of association and dissociation (k(on) and k(off), respectively) of antihistamines have suggested that second-generation antihistamines have...

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Detaylı Bibliyografya
Yayımlandı:Int J Mol Sci
Asıl Yazarlar: Akimoto, Hayato, Uesawa, Yoshihiro, Hishinuma, Shigeru
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957501/
https://ncbi.nlm.nih.gov/pubmed/33673686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052400
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