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Molecular Determinants of the Kinetic Binding Properties of Antihistamines at the Histamine H(1) Receptors

The binding affinity of ligands for their receptors is determined by their kinetic and thermodynamic binding properties. Kinetic analyses of the rate constants of association and dissociation (k(on) and k(off), respectively) of antihistamines have suggested that second-generation antihistamines have...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Akimoto, Hayato, Uesawa, Yoshihiro, Hishinuma, Shigeru
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957501/
https://ncbi.nlm.nih.gov/pubmed/33673686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052400
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