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Phenotypic diversity in ALS and the role of poly-conformational protein misfolding

In many types of familial amyotrophic lateral sclerosis (fALS), mutations cause proteins to gain toxic properties that mediate neurodegenerative processes. It is becoming increasingly clear that the proteins involved in ALS, and those responsible for a host of other neurodegenerative diseases, share...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Ayers, Jacob I., Borchelt, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956917/
https://ncbi.nlm.nih.gov/pubmed/32930869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-020-02222-x
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