Evaluation of Fused Pyrrolothiazole Systems as Correctors of Mutant CFTR Protein

Cystic fibrosis (CF) is a genetic disease caused by mutations that impair the function of the CFTR chloride channel. The most frequent mutation, F508del, causes misfolding and premature degradation of CFTR protein. This defect can be overcome with pharmacological agents named “correctors”. So far, a...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Molecules
Hlavní autoři: Spanò, Virginia, Barreca, Marilia, Cilibrasi, Vincenzo, Genovese, Michele, Renda, Mario, Montalbano, Alessandra, Galietta, Luis Juan Vicente, Barraja, Paola
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956813/
https://ncbi.nlm.nih.gov/pubmed/33652850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26051275
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky