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Are In Vitro Human Blood–Brain–Tumor-Barriers Suitable Replacements for In Vivo Models of Brain Permeability for Novel Therapeutics?

SIMPLE SUMMARY: Brain cancers are a devastating disease with no cure. The aim of the study was to determine whether in vitro models can replace in vivo models to assess the brain permeability of novel drugs for brain cancer. Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyse...

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書誌詳細
出版年:Cancers (Basel)
主要な著者: Prashanth, Archana, Donaghy, Heather, Stoner, Shihani P., Hudson, Amanda L., Wheeler, Helen R., Diakos, Connie I., Howell, Viive M., Grau, Georges E., McKelvey, Kelly J.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956470/
https://ncbi.nlm.nih.gov/pubmed/33668807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13050955
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