Are In Vitro Human Blood–Brain–Tumor-Barriers Suitable Replacements for In Vivo Models of Brain Permeability for Novel Therapeutics?

SIMPLE SUMMARY: Brain cancers are a devastating disease with no cure. The aim of the study was to determine whether in vitro models can replace in vivo models to assess the brain permeability of novel drugs for brain cancer. Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyse...

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書目詳細資料
發表在:Cancers (Basel)
Main Authors: Prashanth, Archana, Donaghy, Heather, Stoner, Shihani P., Hudson, Amanda L., Wheeler, Helen R., Diakos, Connie I., Howell, Viive M., Grau, Georges E., McKelvey, Kelly J.
格式: Artigo
語言:Inglês
出版: MDPI 2021
主題:
Systematic Review
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956470/
https://ncbi.nlm.nih.gov/pubmed/33668807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13050955
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