Glycolysis and Fatty Acid Oxidation Inhibition Improves Survival in Glioblastoma

Glioblastoma (GBM) is the most aggressive adult glioma with a median survival of 14 months. While standard treatments (safe maximal resection, radiation, and temozolomide chemotherapy) have increased the median survival in favorable O(6)-methylguanine-DNA methyltransferase (MGMT)-methylated GBM (~21...

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Udgivet i:Front Oncol
Main Authors: McKelvey, Kelly J., Wilson, Erica B., Short, Susan, Melcher, Alan A., Biggs, Michael, Diakos, Connie I., Howell, Viive M.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039392/
https://ncbi.nlm.nih.gov/pubmed/33854970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.633210
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