Are In Vitro Human Blood–Brain–Tumor-Barriers Suitable Replacements for In Vivo Models of Brain Permeability for Novel Therapeutics?

SIMPLE SUMMARY: Brain cancers are a devastating disease with no cure. The aim of the study was to determine whether in vitro models can replace in vivo models to assess the brain permeability of novel drugs for brain cancer. Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyse...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Prashanth, Archana, Donaghy, Heather, Stoner, Shihani P., Hudson, Amanda L., Wheeler, Helen R., Diakos, Connie I., Howell, Viive M., Grau, Georges E., McKelvey, Kelly J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
Soggetti:
Systematic Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7956470/
https://ncbi.nlm.nih.gov/pubmed/33668807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13050955
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