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Water orientation and dynamics in the closed and open influenza B virus M2 proton channels

The influenza B M2 protein forms a water-filled tetrameric channel to conduct protons across the lipid membrane. To understand how channel water mediates proton transport, we have investigated the water orientation and dynamics using solid-state NMR spectroscopy and molecular dynamics (MD) simulatio...

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Bibliografski detalji
Izdano u:Commun Biol
Glavni autori: Gelenter, Martin D., Mandala, Venkata S., Niesen, Michiel J. M., Sharon, Dina A., Dregni, Aurelio J., Willard, Adam P., Hong, Mei
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955094/
https://ncbi.nlm.nih.gov/pubmed/33712696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-01847-2
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