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Atomic Structures of Closed and Open Influenza B M2 Proton Channel Reveal the Conduction Mechanism
The influenza B M2 (BM2) proton channel is activated by acidic pH to mediate virus uncoating. Unlike influenza A M2 (AM2), which conducts protons with strong inward rectification, BM2 conducts protons both inward and outward. Here we report 1.4- and 1.5-angstrom solid-state NMR structures of the tra...
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| Publié dans: | Nat Struct Mol Biol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7641042/ https://ncbi.nlm.nih.gov/pubmed/32015551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0371-2 |
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