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A Computational Study of the Closed and Open States of the Influenza A M2 Proton Channel

In this study, four possible conformations of the His-37 and Trp-41 residues for the closed state of the influenza M2 ion channel were identified by a conformation scan based on a solid-state NMR restraint. In the four conformations, the His-37 residue can be of either the t-160 or t60 rotamer, wher...

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Autori principali: Wu, Yujie, Voth, Gregory A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biophysical Society 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366740/
https://ncbi.nlm.nih.gov/pubmed/16040757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.066647
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