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Locking CNGA1 Channels in the Open and Closed State

With the aim of understanding the relation between structure and gating of CNGA1 channels from bovine rod, an extensive cysteine scanning mutagenesis was performed. Each residue from Phe-375 to Val-424 was mutated into a cysteine one at a time and the modification caused by various sulfhydryl reagen...

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Detalhes bibliográficos
Main Authors: Nair, Anil V., Mazzolini, Monica, Codega, Paolo, Giorgetti, Alejandro, Torre, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440740/
https://ncbi.nlm.nih.gov/pubmed/16513780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.073346
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