Conformational rearrangements in the transmembrane domain of CNGA1 channels revealed by single-molecule force spectroscopy

Cyclic nucleotide-gated (CNG) channels are activated by binding of cyclic nucleotides. Although structural studies have identified the channel pore and selectivity filter, conformation changes associated with gating remain poorly understood. Here we combine single-molecule force spectroscopy (SMFS)...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Maity, Sourav, Mazzolini, Monica, Arcangeletti, Manuel, Valbuena, Alejandro, Fabris, Paolo, Lazzarino, Marco, Torre, Vincent
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432583/
https://ncbi.nlm.nih.gov/pubmed/25963832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8093
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