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EphA2 super-enhancer promotes tumor progression by recruiting FOSL2 and TCF7L2 to activate the target gene EphA2

Super-enhancers or stretch enhancers (SEs) consist of large clusters of active transcription enhancers which promote the expression of critical genes that define cell identity during development and disease. However, the role of many super-enhancers in tumor cells remains unclear. This study aims to...

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Publicat a:Cell Death Dis
Autors principals: Cui, Shuang, Wu, Qiong, Liu, Ming, Su, Mu, Liu, ShiYou, Shao, Lan, Han, Xiao, He, Hongjuan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955082/
https://ncbi.nlm.nih.gov/pubmed/33712565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03538-6
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