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EphA2 super-enhancer promotes tumor progression by recruiting FOSL2 and TCF7L2 to activate the target gene EphA2

Super-enhancers or stretch enhancers (SEs) consist of large clusters of active transcription enhancers which promote the expression of critical genes that define cell identity during development and disease. However, the role of many super-enhancers in tumor cells remains unclear. This study aims to...

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Podrobná bibliografie
Vydáno v:Cell Death Dis
Hlavní autoři: Cui, Shuang, Wu, Qiong, Liu, Ming, Su, Mu, Liu, ShiYou, Shao, Lan, Han, Xiao, He, Hongjuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955082/
https://ncbi.nlm.nih.gov/pubmed/33712565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03538-6
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