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EphA2 super-enhancer promotes tumor progression by recruiting FOSL2 and TCF7L2 to activate the target gene EphA2

Super-enhancers or stretch enhancers (SEs) consist of large clusters of active transcription enhancers which promote the expression of critical genes that define cell identity during development and disease. However, the role of many super-enhancers in tumor cells remains unclear. This study aims to...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Death Dis
Päätekijät: Cui, Shuang, Wu, Qiong, Liu, Ming, Su, Mu, Liu, ShiYou, Shao, Lan, Han, Xiao, He, Hongjuan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7955082/
https://ncbi.nlm.nih.gov/pubmed/33712565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03538-6
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