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HNO to NO Conversion Mechanism via Copper Zinc Superoxide Dismutase (CuZnSOD), Comparison with Heme Protein Mediated Conversions, and Origin of the Questionable Reversibility
Conversion between NO and HNO via CuZnSOD is important in biomedicine and for HNO detection. Many mechanistic questions, including the decades-long debate on reversibility, were resolved in this work. Calculations of various active site and full protein models show that the basic mechanism is proton...
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| Vydáno v: | Chemistry |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7954974/ https://ncbi.nlm.nih.gov/pubmed/33398888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202100015 |
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