Copper chaperone for superoxide dismutase is essential to activate mammalian Cu/Zn superoxide dismutase

Recent studies in Saccharomyces cerevisiae suggest that the delivery of copper to Cu/Zn superoxide dismutase (SOD1) is mediated by a cytosolic protein termed the copper chaperone for superoxide dismutase (CCS). To determine the role of CCS in mammalian copper homeostasis, we generated mice with targ...

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Detalhes bibliográficos
Main Authors: Wong, Philip C., Waggoner, Darrel, Subramaniam, Jamuna R., Tessarollo, Lino, Bartnikas, Thomas B., Culotta, Valeria C., Price, Donald L., Rothstein, Jeffrey, Gitlin, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16025/
https://ncbi.nlm.nih.gov/pubmed/10694572
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