Cyclophilin 19 secreted in the host cell cytosol by Trypanosoma cruzi promotes ROS production required for parasite growth

Infection by Trypanosoma cruzi, the protozoan parasite that causes Chagas disease, depends on reactive oxygen species (ROS), which has been described to induce parasite proliferation in mammalian host cells. It is unknown how the parasite manages to increase host ROS levels. Here, we found that intr...

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Bibliografiska uppgifter
I publikationen:Cell Microbiol
Huvudupphovsmän: dos Santos, Gregory Pedroso, Abukawa, Fernanda Midori, Souza-Melo, Normanda, Alcântara, Laura Maria, Bittencourt-Cunha, Paula, Moraes, Carolina Borsoi, Jha, Bijay Kumar, McGwire, Bradford S., Moretti, Nilmar Silvio, Schenkman, Sergio
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954913/
https://ncbi.nlm.nih.gov/pubmed/33222354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.13295
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