Trypanosoma cruzi GP63 Proteins Undergo Stage-Specific Differential Posttranslational Modification and Are Important for Host Cell Infection

The protozoan Trypanosoma cruzi expresses multiple isoforms of the GP63 family of metalloproteases. Polyclonal antiserum against recombinant GP63 of T. cruzi (TcGP63) was used to study TcGP63 expression and localization in this organism. Western blot analysis revealed that TcGP63 is 61 kDa in epimas...

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Bibliographic Details
Main Authors: Kulkarni, Manjusha M., Olson, Cheryl L., Engman, David M., McGwire, Bradford S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681764/
https://ncbi.nlm.nih.gov/pubmed/19273559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01542-08
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