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Cyclophilin 19 secreted in the host cell cytosol by Trypanosoma cruzi promotes ROS production required for parasite growth

Infection by Trypanosoma cruzi, the protozoan parasite that causes Chagas disease, depends on reactive oxygen species (ROS), which has been described to induce parasite proliferation in mammalian host cells. It is unknown how the parasite manages to increase host ROS levels. Here, we found that intr...

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Bibliografiske detaljer
Udgivet i:Cell Microbiol
Main Authors: dos Santos, Gregory Pedroso, Abukawa, Fernanda Midori, Souza-Melo, Normanda, Alcântara, Laura Maria, Bittencourt-Cunha, Paula, Moraes, Carolina Borsoi, Jha, Bijay Kumar, McGwire, Bradford S., Moretti, Nilmar Silvio, Schenkman, Sergio
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954913/
https://ncbi.nlm.nih.gov/pubmed/33222354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.13295
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