Identification of Inhibitors to Trypanosoma cruzi Sirtuins Based on Compounds Developed to Human Enzymes

Chagas disease is an illness caused by the protozoan parasite Trypanosoma cruzi, affecting more than 7 million people in the world. Benznidazole and nifurtimox are the only drugs available for treatment and in addition to causing several side effects, are only satisfactory in the acute phase of the...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Matutino Bastos, Tanira, Botelho Pereira Soares, Milena, Haddad Franco, Caio, Alcântara, Laura, Antonini, Lorenzo, Sabatino, Manuela, Mautone, Nicola, Holanda Freitas-Junior, Lucio, Moraes, Carolina Borsoi, Ragno, Rino, Rotili, Dante, Schenkman, Sergio, Mai, Antonello, Silvio Moretti, Nilmar
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279216/
https://ncbi.nlm.nih.gov/pubmed/32455951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21103659
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