Human TERT promoter mutations as a prognostic biomarker in glioma

The TERT promoter (pTERT) mutations, C228T and C250T, play a significant role in malignant transformation by telomerase activation, oncogenesis and immortalisation of cells. C228T and C250T are emerging as important biomarkers in many cancers including glioblastoma multiforme (GBM), where the preval...

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Gepubliceerd in:J Cancer Res Clin Oncol
Hoofdauteurs: Powter, Branka, Jeffreys, Sarah A., Sareen, Heena, Cooper, Adam, Brungs, Daniel, Po, Joseph, Roberts, Tara, Koh, Eng-Siew, Scott, Kieran F., Sajinovic, Mila, Vessey, Joey Y., de Souza, Paul, Becker, Therese M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Berlin Heidelberg 2021
Onderwerpen:
Review – Cancer Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954705/
https://ncbi.nlm.nih.gov/pubmed/33547950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-021-03536-3
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