Human TERT promoter mutations as a prognostic biomarker in glioma

The TERT promoter (pTERT) mutations, C228T and C250T, play a significant role in malignant transformation by telomerase activation, oncogenesis and immortalisation of cells. C228T and C250T are emerging as important biomarkers in many cancers including glioblastoma multiforme (GBM), where the preval...

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Bibliographic Details
Published in:J Cancer Res Clin Oncol
Main Authors: Powter, Branka, Jeffreys, Sarah A., Sareen, Heena, Cooper, Adam, Brungs, Daniel, Po, Joseph, Roberts, Tara, Koh, Eng-Siew, Scott, Kieran F., Sajinovic, Mila, Vessey, Joey Y., de Souza, Paul, Becker, Therese M.
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2021
Subjects:
Review – Cancer Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954705/
https://ncbi.nlm.nih.gov/pubmed/33547950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-021-03536-3
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