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The frequency and prognostic effect of TERT promoter mutation in diffuse gliomas

Mutations in the telomerase reverse transcriptase gene promoter (TERTp) are common in glioblastomas (GBMs) and oligodendrogliomas (ODGs), and therefore, have a key role in tumorigenesis and may be of prognostic value. However, the extent of their prognostic importance in various gliomas is controver...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Lee, Yujin, Koh, Jaemoon, Kim, Seong-Ik, Won, Jae Kyung, Park, Chul-Kee, Choi, Seung Hong, Park, Sung-Hye
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574236/
https://ncbi.nlm.nih.gov/pubmed/28851427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0465-1
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