Human TERT promoter mutations as a prognostic biomarker in glioma

The TERT promoter (pTERT) mutations, C228T and C250T, play a significant role in malignant transformation by telomerase activation, oncogenesis and immortalisation of cells. C228T and C250T are emerging as important biomarkers in many cancers including glioblastoma multiforme (GBM), where the preval...

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Detalhes bibliográficos
Publicado no:J Cancer Res Clin Oncol
Main Authors: Powter, Branka, Jeffreys, Sarah A., Sareen, Heena, Cooper, Adam, Brungs, Daniel, Po, Joseph, Roberts, Tara, Koh, Eng-Siew, Scott, Kieran F., Sajinovic, Mila, Vessey, Joey Y., de Souza, Paul, Becker, Therese M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2021
Assuntos:
Review – Cancer Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954705/
https://ncbi.nlm.nih.gov/pubmed/33547950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-021-03536-3
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