Human TERT promoter mutations as a prognostic biomarker in glioma

The TERT promoter (pTERT) mutations, C228T and C250T, play a significant role in malignant transformation by telomerase activation, oncogenesis and immortalisation of cells. C228T and C250T are emerging as important biomarkers in many cancers including glioblastoma multiforme (GBM), where the preval...

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Vydáno v:J Cancer Res Clin Oncol
Hlavní autoři: Powter, Branka, Jeffreys, Sarah A., Sareen, Heena, Cooper, Adam, Brungs, Daniel, Po, Joseph, Roberts, Tara, Koh, Eng-Siew, Scott, Kieran F., Sajinovic, Mila, Vessey, Joey Y., de Souza, Paul, Becker, Therese M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2021
Témata:
Review – Cancer Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954705/
https://ncbi.nlm.nih.gov/pubmed/33547950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-021-03536-3
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