Human TERT promoter mutations as a prognostic biomarker in glioma

The TERT promoter (pTERT) mutations, C228T and C250T, play a significant role in malignant transformation by telomerase activation, oncogenesis and immortalisation of cells. C228T and C250T are emerging as important biomarkers in many cancers including glioblastoma multiforme (GBM), where the preval...

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Dades bibliogràfiques
Publicat a:J Cancer Res Clin Oncol
Autors principals: Powter, Branka, Jeffreys, Sarah A., Sareen, Heena, Cooper, Adam, Brungs, Daniel, Po, Joseph, Roberts, Tara, Koh, Eng-Siew, Scott, Kieran F., Sajinovic, Mila, Vessey, Joey Y., de Souza, Paul, Becker, Therese M.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2021
Matèries:
Review – Cancer Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954705/
https://ncbi.nlm.nih.gov/pubmed/33547950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-021-03536-3
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