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TorsinA restoration in a mouse model identifies a critical therapeutic window for DYT1 dystonia
In inherited neurodevelopmental diseases, pathogenic processes unique to critical periods during early brain development may preclude the effectiveness of gene modification therapies applied later in life. We explored this question in a mouse model of DYT1 dystonia, a neurodevelopmental disease caus...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7954593/ https://ncbi.nlm.nih.gov/pubmed/33529159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI139606 |
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