Cargando...
DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7
The committed step of eukaryotic DNA replication occurs when the pairs of Mcm2-7 replicative helicases that license each replication origin are activated. Helicase activation requires the recruitment of Cdc45 and GINS to Mcm2-7, forming Cdc45-Mcm2-7-GINS complexes (CMGs). Using single-molecule bioch...
Guardado en:
| Publicado en: | eLife |
|---|---|
| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2021
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7954526/ https://ncbi.nlm.nih.gov/pubmed/33616038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.65471 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|