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Surface-directed engineering of tissue anisotropy in microphysiological models of musculoskeletal tissue

Here, we present an approach to model and adapt the mechanical regulation of morphogenesis that uses contractile cells as sculptors of engineered tissue anisotropy in vitro. Our method uses heterobifunctional cross-linkers to create mechanical boundary constraints that guide surface-directed sculpti...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Adv
Päätekijät: Mondrinos, Mark J., Alisafaei, Farid, Yi, Alex Y., Ahmadzadeh, Hossein, Lee, Insu, Blundell, Cassidy, Seo, Jeongyun, Osborn, Matthew, Jeon, Tae-Joon, Kim, Sun Min, Shenoy, Vivek B., Huh, Dongeun
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Association for the Advancement of Science 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954445/
https://ncbi.nlm.nih.gov/pubmed/33712463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe9446
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