Surface-directed engineering of tissue anisotropy in microphysiological models of musculoskeletal tissue

Here, we present an approach to model and adapt the mechanical regulation of morphogenesis that uses contractile cells as sculptors of engineered tissue anisotropy in vitro. Our method uses heterobifunctional cross-linkers to create mechanical boundary constraints that guide surface-directed sculpti...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Adv
Main Authors: Mondrinos, Mark J., Alisafaei, Farid, Yi, Alex Y., Ahmadzadeh, Hossein, Lee, Insu, Blundell, Cassidy, Seo, Jeongyun, Osborn, Matthew, Jeon, Tae-Joon, Kim, Sun Min, Shenoy, Vivek B., Huh, Dongeun
Format: Artigo
Jezik:Inglês
Izdano: American Association for the Advancement of Science 2021
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954445/
https://ncbi.nlm.nih.gov/pubmed/33712463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe9446
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