Surface-directed engineering of tissue anisotropy in microphysiological models of musculoskeletal tissue

Here, we present an approach to model and adapt the mechanical regulation of morphogenesis that uses contractile cells as sculptors of engineered tissue anisotropy in vitro. Our method uses heterobifunctional cross-linkers to create mechanical boundary constraints that guide surface-directed sculpti...

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Vydáno v:Sci Adv
Hlavní autoři: Mondrinos, Mark J., Alisafaei, Farid, Yi, Alex Y., Ahmadzadeh, Hossein, Lee, Insu, Blundell, Cassidy, Seo, Jeongyun, Osborn, Matthew, Jeon, Tae-Joon, Kim, Sun Min, Shenoy, Vivek B., Huh, Dongeun
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2021
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954445/
https://ncbi.nlm.nih.gov/pubmed/33712463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe9446
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