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A novel multimeric IL15/IL15Rα-Fc complex to enhance cancer immunotherapy

The role of T cells in controlling human cancers is well known. Their success requires continued persistence in vivo and efficient trafficking to tumor sites, requirements shared by other effectors such as Natural Killer (NK) cells. To date, cytokine IL2 remains the only clinically approved cytokine...

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Publicat a:Oncoimmunology
Autors principals: Xu, Hong, Buhtoiarov, Ilia N., Guo, Hongfen, Cheung, Nai-Kong V.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7954438/
https://ncbi.nlm.nih.gov/pubmed/33763293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2021.1893500
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