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Lack of NFATc1 SUMOylation prevents autoimmunity and alloreactivity
Posttranslational modification with SUMO is known to regulate the activity of transcription factors, but how SUMOylation of individual proteins might influence immunity is largely unexplored. The NFAT transcription factors play an essential role in antigen receptor-mediated gene regulation. SUMOylat...
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| 出版年: | J Exp Med |
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| 主要な著者: | , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Rockefeller University Press
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7953626/ https://ncbi.nlm.nih.gov/pubmed/32986812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181853 |
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