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Lack of NFATc1 SUMOylation prevents autoimmunity and alloreactivity
Posttranslational modification with SUMO is known to regulate the activity of transcription factors, but how SUMOylation of individual proteins might influence immunity is largely unexplored. The NFAT transcription factors play an essential role in antigen receptor-mediated gene regulation. SUMOylat...
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| Publicado no: | J Exp Med |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7953626/ https://ncbi.nlm.nih.gov/pubmed/32986812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181853 |
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