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Single-molecule view of coordination in a multi-functional DNA polymerase

Replication and repair of genomic DNA requires the actions of multiple enzymatic functions that must be coordinated in order to ensure efficient and accurate product formation. Here, we have used single-molecule FRET microscopy to investigate the physical basis of functional coordination in DNA poly...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Pauszek, Raymond F, Lamichhane, Rajan, Rajkarnikar Singh, Arishma, Millar, David P
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2021
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952088/
https://ncbi.nlm.nih.gov/pubmed/33704066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.62046
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