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Single-molecule view of coordination in a multi-functional DNA polymerase

Replication and repair of genomic DNA requires the actions of multiple enzymatic functions that must be coordinated in order to ensure efficient and accurate product formation. Here, we have used single-molecule FRET microscopy to investigate the physical basis of functional coordination in DNA poly...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Pauszek, Raymond F, Lamichhane, Rajan, Rajkarnikar Singh, Arishma, Millar, David P
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7952088/
https://ncbi.nlm.nih.gov/pubmed/33704066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.62046
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