IGF2BP1 is a targetable SRC/MAPK-dependent driver of invasive growth in ovarian cancer

Epithelial-to-mesenchymal transition (EMT) is a hallmark of aggressive, mesenchymal-like high-grade serous ovarian carcinoma (HGSOC). The SRC kinase is a key driver of cancer-associated EMT promoting adherens junction (AJ) disassembly by phosphorylation-driven internalization and degradation of AJ p...

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Bibliografiske detaljer
Udgivet i:RNA Biol
Main Authors: Bley, Nadine, Schott, Annekatrin, Müller, Simon, Misiak, Danny, Lederer, Marcell, Fuchs, Tommy, Aßmann, Chris, Glaß, Markus, Ihling, Christian, Sinz, Andrea, Pazaitis, Nikolaos, Wickenhauser, Claudia, Vetter, Martina, Ungurs, Olga, Strauss, Hans-Georg, Thomssen, Christoph, Hüttelmaier, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7951963/
https://ncbi.nlm.nih.gov/pubmed/32876513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2020.1812894
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