IGF2BP1, a Conserved Regulator of RNA Turnover in Cancer

The oncofetal IGF2 mRNA-binding protein 1 (IGF2BP1) promotes tumor progression in a variety of solid tumors and its expression is associated with adverse prognosis. The main role proposed for IGF2BP1 in cancer cells is the stabilization of mRNAs encoding pro-oncogenic factors. Several IGF2BP1-RNA as...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Glaß, Markus, Misiak, Danny, Bley, Nadine, Müller, Simon, Hagemann, Sven, Busch, Bianca, Rausch, Alexander, Hüttelmaier, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Molecular Biosciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8019740/
https://ncbi.nlm.nih.gov/pubmed/33829040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.632219
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