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Tet1 is not required for myeloid leukemogenesis by MLL-ENL in novel mouse models
The Ten Eleven Translocation 1 (TET1) gene encodes an epigenetic modifying molecule that is involved in demethylation of 5-methylcytosine. In hematological malignancies, loss-of-function mutations of TET2, which is one of the TET family genes including TET1, are frequently found, while the mutations...
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| Опубликовано в: : | PLoS One |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7951824/ https://ncbi.nlm.nih.gov/pubmed/33705482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0248425 |
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