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Eya2, a Target Activated by Plzf, Is Critical for PLZF-RARA-Induced Leukemogenesis

PLZF is a transcription factor that confers aberrant self-renewal in leukemogenesis, and the PLZF-RARA fusion gene causes acute promyelocytic leukemia (APL) through differentiation block. However, the molecular mechanisms of aberrant self-renewal underlying PLZF-mediated leukemogenesis are poorly un...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Ono, Ryoichi, Masuya, Masahiro, Ishii, Satomi, Katayama, Naoyuki, Nosaka, Tetsuya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472835/
https://ncbi.nlm.nih.gov/pubmed/28416638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00585-16
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