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Characterisation of Genome-Wide PLZF/RARA Target Genes

The PLZF/RARA fusion protein generated by the t(11;17)(q23;q21) translocation in acute promyelocytic leukaemia (APL) is believed to act as an oncogenic transcriptional regulator recruiting epigenetic factors to genes important for its transforming potential. However, molecular mechanisms associated...

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Detalhes bibliográficos
Main Authors: Spicuglia, Salvatore, Vincent-Fabert, Christelle, Benoukraf, Touati, Tibéri, Guillaume, Saurin, Andrew J., Zacarias-Cabeza, Joaquin, Grimwade, David, Mills, Ken, Calmels, Boris, Bertucci, François, Sieweke, Michael, Ferrier, Pierre, Duprez, Estelle
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176768/
https://ncbi.nlm.nih.gov/pubmed/21949697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024176
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